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Visomitin (SKQ1) is a novel mitochondrial (mitochondrial) targeted antioxidant that holds promise for the treatment of inflammation associated with ocular surface diseases such as dry eye disease (DED) and corneal wounds. SkQ1 displays TC50 at 317 nM on HCjE cells.
Brand: BCM
Target: Reactive Oxygen Species
Signaling Pathways: Metabolism; NF-κB; Immunology/Inflammation
Solubility: Soluble in DMSO.
GHS: GHS02,GHS07
Isomeric SMILES: CC1=C(C(=O)C(=CC1=O)CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]
InChIKey: WYHFWTRUGAFNKW-UHFFFAOYSA-M
InChI: InChI=1S/C36H42O2P.BrH/c1-29-30(2)36(38)31(28-35(29)37)20-12-7-5-3-4-6-8-19-27-39(32-21-13-9-14-22-32,33-23-15-10-16-24-33)34-25-17-11-18-26-34;/h9-11,13-18,21-26,28H,3-8,12,19-20,27H2,1-2H3;1H/q+1;/p-1
Attribute [Chem Name] 10-(4,5-dimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl-triphenylphosphanium;bromide [Synonym] Visomitin (SKQ1); SKQ1 [CAS No.] 934826-68-3 [EINECS] 604-604-1 [MDL No.] MFCD29477502 [Formula] C36H42BrO2P [Molecular] 617.62 [Form] Brown solid [Storage] Inert atmosphere. Store in freezer, under -20°C
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