Honokiol (NSC 293100), an active component of Magnolia magnolia, inhibits Akt phosphorylation and promotes ERK1/2 phosphorylation. Honokiol can cause G0/G1 phase block and induce apoptosis and autophagy through ROS/ERK1/2 signaling pathway. Honokiol inhibits hepatitis C virus (HCV) infection. Phase 3.

 

Brand: BCM

 

Target: HCV Protease; ERK; MEK; Akt; Autophagy

 

Signaling Pathways: Autophagy; Cytoskeletal Signaling; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome

 

Melting Point: 86°C

 

Boiling Point: 400.1°C at 760 mmHg

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Sensitivity: Light Sensitive

 

GHS: GHS05, GHS09

 

Isomeric SMILES: C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C  

 

InChIKey: FVYXIJYOAGAUQK-UHFFFAOYSA-N  

 

InChI: InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2

 

Attribute
[Chem Name]	2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol
[Synonym]	Honokiol; NSC 293100
[CAS No.]	35354-74-6
[EINECS]	609-119-8
[MDL No.]	MFCD00016674
[Formula]	C18H18O2
[Molecular]	266.33
[Form]	White to Off-White Powder
[Risk Codes]	H318-H411
[Storage]	Sealed in dry, 2-8°C

Goods Tag