IMR-1 is a novel Notch inhibitor targeting transcriptional activation with an IC50 of 26 μM.

 

Brand: BCM

 

Target: Notch:6 μMol/L

 

Signaling Pathways: Neuroscience; Proteases/Proteasome; Stem Cells

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

GHS: GHS07

 

Isomeric SMILES: CCOC(=O)COC1=C(C=C(C=C1)/C=C/2\C(=O)NC(=S)S2)OC  

 

InChIKey: QHPJWPQRZMBKTG-KPKJPENVSA-N  

 

InChI: InChI=1S/C15H15NO5S2/c1-3-20-13(17)8-21-10-5-4-9(6-11(10)19-2)7-12-14(18)16-15(22)23-12/h4-7H,3,8H2,1-2H3,(H,16,18,22)/b12-7+

 

Attribute
[Chem Name]	ethyl 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetate
[Synonym]	IMR-1
[CAS No.]	310456-65-6
[MDL No.]	MFCD04141288
[Formula]	C15H15NO5S2
[Molecular]	353.41
[Form]	Yellow solid
[Risk Codes]	H302-H315-H319-H335
[Storage]	Keep in dark place. Sealed in dry, 2-8°C

Goods Tag