GW6340 is a gut-specific LXR agonist. GW6340 promotes macrophage reverse cholesterol transport (mRCT).

 

Brand: BCM

 

Target: LXR

 

Boiling Point: 696.5±55.0 °C(Predicted)

 

pKa: 16.14±0.40(Predicted)

 

Isomeric SMILES: O=C(CC1=CC(OCCCN(CC(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC=CC(C(F)(F)F)=C4Cl)=CC=C1)N

 

InChIKey: ZVWVNNYZOBNFFJ-UHFFFAOYSA-N

 

InChI: InChI=1S/C33H32ClF3N2O2/c34-32-27(15-8-17-30(32)33(35,36)37)22-39(18-9-19-41-28-16-7-10-24(20-28)21-31(38)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H2,38,40)

 

Attribute
[Chem Name]	2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetamide
[Synonym]	GW6340; GW 6340; GW-6340
[CAS No.]	405910-78-3
[Formula]	C33H32ClF3N2O2
[Molecular]	581.07

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