Fisetin is a potent Sirtuin activating compound (STAC) that regulates Sirtuin. It is a natural flavonol found in many fruits and vegetables and has antioxidant, anti-cancer and neuroprotective effects.

 

Brand: BCM

 

Target: TNF; Sirtuin; PPAR

 

Signaling Pathways: Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism

 

In Vitro: Fisetin selectively kills SPiDER-β-Gal positive senescence neural cells in vitro.

 

Melting Point: >330 °C(lit.)

 

Boiling Point: 348.61°C (rough estimate)

 

pKa: 6.83±0.40(Predicted)

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O  

 

InChIKey: XHEFDIBZLJXQHF-UHFFFAOYSA-N  

 

InChI: InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H

 

Attribute
[Chem Name]	2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one
[Synonym]	Fisetin
[CAS No.]	528-48-3
[EINECS]	208-434-4
[MDL No.]	MFCD00006829
[Formula]	C15H10O6
[Molecular]	286.24
[Form]	Pale Yellow to Very Dark Yellow Solid
[Storage]	Sealed in dry. Store in freezer, under -20°C

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