BMF-219 is a novel, potent and irreversible menin inhibitor that can be used to treat leukemia.

 

Brand: BCM

 

pKa: 11.80±0.70(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: C=CC(=O)N[C@@H]1CCCN(C1)CC2=CC(=NC=C2)C(=O)NC3=CC=C(C=C3)C4=CC5=C(N4)N=CN=C5N6CCOCC6  

 

InChIKey: CPRLHPSXWZTPMC-XMMPIXPASA-N  

 

InChI: InChI=1S/C31H34N8O3/c1-2-28(40)35-24-4-3-11-38(19-24)18-21-9-10-32-27(16-21)31(41)36-23-7-5-22(6-8-23)26-17-25-29(37-26)33-20-34-30(25)39-12-14-42-15-13-39/h2,5-10,16-17,20,24H,1,3-4,11-15,18-19H2,(H,35,40)(H,36,41)(H,33,34,37)/t24-/m1/s1

 

Attribute
[Chem Name]	N-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-4-[[(3R)-3-(prop-2-enoylamino)piperidin-1-yl]methyl]pyridine-2-carboxamide
[Synonym]	BMF-219; Menin-MLL Inhibitor 21
[CAS No.]	2448172-22-1
[Formula]	C31H34N8O3
[Molecular]	566.65
[Form]	Solid powder
[Storage]	Stored at -20°C

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