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KY02111 inhibits Wnt signaling and promotes the differentiation of hPSCs into cardiomyocytes, which may have an effect on the downstream of APC and GSK3β.
Brand: BCM
Target: Wnt/beta-catenin
Signaling Pathways: Cytoskeletal Signaling; Stem Cells
pKa: 9.92±0.70(Predicted)
Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.
GHS: GHS07
Isomeric SMILES: COC1=C(C=C(C=C1)CCC(=O)NC2=NC3=C(S2)C=C(C=C3)Cl)OC
InChIKey: LXFKEVQQSKQXPR-UHFFFAOYSA-N
InChI: InChI=1S/C18H17ClN2O3S/c1-23-14-7-3-11(9-15(14)24-2)4-8-17(22)21-18-20-13-6-5-12(19)10-16(13)25-18/h3,5-7,9-10H,4,8H2,1-2H3,(H,20,21,22)
Attribute [Chem Name] N-(6-chloro-1,3-benzothiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide [Synonym] KY02111; KY-02111; KY 02111 [CAS No.] 1118807-13-8 [EINECS] 808-505-5 [MDL No.] MFCD08483062 [Formula] C18H17ClN2O3S [Molecular] 376.86 [Form] White to beige powder [Storage] Sealed in dry, 2-8°C
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