Mc-val-cit-pb-pnp (Mc-val-cit-pbc-pnp) is a cleavable cathepsin ADC peptide linker that can be used to synthesize antiboy-conjugated drugs (ADCs).

 

Brand: BCM

 

Target: Others; AChR

 

Signaling Pathways: Neuroscience; Others

 

Boiling Point: 1034.5±65.0 °C at 760 mmHg

 

Flashing Point: 579.4±34.3 °C

 

Vapour Pressure: 0.0±0.3 mmHg at 25°C

 

pKa: 13.24±0.70(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CCCCCN3C(=O)C=CC3=O  

 

InChIKey: HYSPJPGXSALJRR-DHIFEGFHSA-N  

 

InChI: InChI=1S/C35H43N7O11/c1-22(2)31(40-28(43)8-4-3-5-20-41-29(44)17-18-30(41)45)33(47)39-27(7-6-19-37-34(36)48)32(46)38-24-11-9-23(10-12-24)21-52-35(49)53-26-15-13-25(14-16-26)42(50)51/h9-18,22,27,31H,3-8,19-21H2,1-2H3,(H,38,46)(H,39,47)(H,40,43)(H3,36,37,48)/t27-,31-/m0/s1

 

Attribute
[Chem Name]	Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate
[Synonym]	MC-VC-PAB-PNP; Mc-Val-Cit-PABC-PNP; Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate
[CAS No.]	159857-81-5
[MDL No.]	MFCD22200431
[Formula]	C35H43N7O11
[Molecular]	737.76
[Storage]	Inert atmosphere, 2-8°C
[Form]	White solid powder

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