Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM to inhibit FTO demethylation.

 

Brand: BCM

 

Target: FTO:<1 μM (IC50)

 

pKa: 8.72±0.40(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: CC1=C(C(=NN1)C)C2=CC(=C(C(=C2)Cl)NC3=CC=CC=C3C(=O)NO)Cl  

 

InChIKey: UMQKDDMRCQAIGA-UHFFFAOYSA-N  

 

InChI: InChI=1S/C18H16Cl2N4O2/c1-9-16(10(2)23-22-9)11-7-13(19)17(14(20)8-11)21-15-6-4-3-5-12(15)18(25)24-26/h3-8,21,26H,1-2H3,(H,22,23)(H,24,25)

 

Attribute
[Chem Name]	2-[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)anilino]-N-hydroxybenzamide
[Synonym]	Dac51; FTO-IN-1; UUN44923
[CAS No.]	2243944-92-3
[MDL No.]	MFCD34473341
[Formula]	C18H16Cl2N4O2
[Molecular]	391.25
[Form]	Solid Powder
[Storage]	Sealed in dry. Stored at -20°C

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