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AR-42 (HDAC-42) is an HDAC inhibitor with an IC50 of 30 nM. Phase 1.
Brand: BCM
Target: HDAC
Signaling Pathways: Chromatin/Epigenetic; DNA Damage/DNA Repair
pKa: 8.94±0.10(Predicted)
Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.
GHS: GHS07
Isomeric SMILES: CC(C)[C@@H](C1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)C(=O)NO
InChIKey: LAMIXXKAWNLXOC-INIZCTEOSA-N
InChI: InChI=1S/C18H20N2O3/c1-12(2)16(13-6-4-3-5-7-13)18(22)19-15-10-8-14(9-11-15)17(21)20-23/h3-12,16,23H,1-2H3,(H,19,22)(H,20,21)/t16-/m0/s1
Attribute [Chem Name] N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide [Synonym] AR-42; HDAC-42; [CAS No.] 935881-37-1 [EINECS] 802-219-4 [MDL No.] MFCD17676151 [Formula] C18H20N2O3 [Molecular] 312.36 [Form] Solid Powder [Storage] Inert atmosphere. Store in freezer, under -20°C
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