Muvalaplin(LY3473329) is an oral small molecule that inhibits lipoprotein (a) (Lp (a)) formation by blocking the apo(a)-apo B100 interaction. It can be used in the study of atherosclerotic diseases and aortic stenosis.

 

Brand: BCM

 

Boiling Point: 863.9±60.0 °C(Predicted)

 

pKa: 3.79±0.10(Predicted)

 

Solubility: Insoluble in DMSO; insoluble in  Water; insoluble in Ethanol.

 

Isomeric SMILES: C1CNC[C@H]1[C@H](CC2=CC(=CC=C2)CN(CC3=CC=CC(=C3)C[C@@H]([C@H]4CCNC4)C(=O)O)CC5=CC=CC(=C5)C[C@@H]([C@H]6CCNC6)C(=O)O)C(=O)O  

 

InChIKey: BRLGERLDHZRETI-BGBFCPIGSA-N  

 

InChI: InChI=1S/C42H54N4O6/c47-40(48)37(34-10-13-43-22-34)19-28-4-1-7-31(16-28)25-46(26-32-8-2-5-29(17-32)20-38(41(49)50)35-11-14-44-23-35)27-33-9-3-6-30(18-33)21-39(42(51)52)36-12-15-45-24-36/h1-9,16-18,34-39,43-45H,10-15,19-27H2,(H,47,48)(H,49,50)(H,51,52)/t34-,35-,36-,37-,38-,39-/m0/s1

 

Attribute
[Chem Name]	(2S)-3-[3-[[bis[[3-[(2S)-2-carboxy-2-[(3R)-pyrrolidin-3-yl]ethyl]phenyl]methyl]amino]methyl]phenyl]-2-[(3R)-pyrrolidin-3-yl]propanoic acid
[Synonym]	Muvalaplin; LY3473329
[CAS No.]	2565656-70-2
[Formula]	C42H54N4O6
[Molecular]	710.9
[Form]	Solid Powder
[Storage]	Sealed in dry. Stored at -20°C.

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