UCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of about 60 μM. UCL-TRO-1938 can induce cell proliferation and has cardioprotective and nerve regeneration effects.

 

Brand: BCM

 

Boiling Point: 677.0±55.0 °C(Predicted)

 

pKa: 8.22±0.10(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Ethanol; Insoluble in Water.

 

Isomeric SMILES: CCN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=CC(=C3)NC4=CC=CC5=C4N(CC5)C(=O)C  

 

InChIKey: RPOHONUDGBSZDK-UHFFFAOYSA-N  

 

InChI: InChI=1S/C27H32N6O/c1-3-31-15-17-32(18-16-31)24-9-7-22(8-10-24)30-26-19-23(11-13-28-26)29-25-6-4-5-21-12-14-33(20(2)34)27(21)25/h4-11,13,19H,3,12,14-18H2,1-2H3,(H2,28,29,30) 

 

Attribute
[Chem Name]	1-[7-[[2-[4-(4-ethylpiperazin-1-yl)anilino]pyridin-4-yl]amino]-2,3-dihydroindol-1-yl]ethanone
[Synonym]	UCL-TRO-1938
[CAS No.]	2919575-27-0
[Formula]	C27H32N6O
[Molecular]	456.58
[Form]	Solid Powder
[Storage]	Sealed in dry. Stored at -20°C.

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