Encorafenib (LGX818) is a highly effective RAF inhibitor that acts on cells expressing B-RAF(V600E) with selective anti-proliferation and apoptotic activity. EC50 is 4 nM. Phase 3.

 

Brand: BCM

 

Melting Point: 184-185°C

 

pKa: 5.94±0.10(Predicted)

 

Solubility: DMSO (Slightly), Methanol (Slightly), Water(Insoluble)

 

Attribute
[CAS No.]	1269440-17-6
[MDL No.]	MFCD25976758
[Formula]	C22H27ClFN7O4S
[Molecular]	540.01
[Chem Name]	Methyl N-[(2s)-1-[[4-[3-[5-chloro-2-fluoro-3-(methanesulfonamido)phenyl]-1-propan-2-ylpyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate
[Synonym]	LGX818; LGX-818; Encorafenib
[Storage]	-20°C Freezer. Under inert atmosphere
[Form]	White to Off-White Solid

Goods Tag