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K03861 is a type II CDK2 inhibitor, acting on CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C) with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM, respectively.
Brand: BCM
Solubility: ≥50.2 mg/mL in DMSO; insoluble in H2O; ≥45.4 mg/mL in EtOH
Attribute [CAS No.] 853299-07-7 [Formula] C24H26F3N7O2 [Molecular] 501.50400 [MDL No.] MFCD19443769 [Form] Solid [Chem Name] 1-[4-(2-aminopyrimidine-4-yloxy)phenyl]-3-[4-(4-methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]urea; [Synonym] AUZ-454; K03861
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