KW-2449 is A multi-target inhibitor, most effective against Flt3 with IC50 of 6.6 nM and moderately effective against Flt3, Bcr-Abl and Aurora A. There was no inhibitory effect on PDGFRβ, IGF-1R, EGFR. Phase 1.

 

Brand: BCM

 

Bpiling Point: 604.1±55.0 °C(Predicted)

 

pKa: 13.76±0.40(Predicted)

 

Solubility: Soluble in DMSO (>25 mg/ml)

 

Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

 

Attribute
[CAS No.]	1000669-72-6
[Formula]	C20H20N4O
[Molecular]	332.4
[Chem Name]	[4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone
[Synonym]	KW 2449; KW-2449; KW2449
[Form]	Pale yellow solid
[Storage]	-20°C
[MDL No.]	MFCD18385006

Goods Tag