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Retigabine 2HCl (D-23129) is a novel anticonvulsant with activity in a wide range of convulsive models. The main mechanism of its activity is the opening of KCNQ2-5 voltage-gated potassium ion channels in neurons.
Brand: BCM
Melting Point: 168-170°C
Stability: Hygroscopic
Solubility: Soluble in DMSO; soluble in Ethanol; soluble in Water.
Isomeric SMILES: CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N.Cl.Cl
InChIKey: WSGFOWNASITQHJ-UHFFFAOYSA-N
InChI: InChI=1S/C16H18FN3O2.2ClH/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11;;/h3-9,19H,2,10,18H2,1H3,(H,20,21);2*1H
Attribute [CAS No.] 150812-13-8 [Formula] C16H20Cl2FN3O2 [Molecular] 339.79 [Chem Name] ethyl N-[2-amino-4-[(4-fluorophenyl)methylamino]phenyl]carbamate;dihydrochloride [Synonym] Retigabine Dihydrochloride; Retigabine 2HCl; D-23129 2HCl [Storage] Hygroscopic, -20°C Freezer. Under Inert Atmosphere [EINECS] 2017-001-1 [MDL No.] MFCD00912289 [Form] Solid
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