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Retigabine (D-23129) is a novel anticonvulsant with activity in a wide range of convulsive models. The main mechanism of its activity is the opening of KCNQ2-5 voltage-gated potassium ion channels in neurons.
Brand: BCM
Boiling Point: 430.0±45.0 °C(Predicted)
Flashing Point: 2°C
pKa: 13.12±0.70(Predicted)
Stability: Hygroscopic
Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.
GHS: GHS06, GHS09
Isomeric SMILES: CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N
InChIKey: PCOBBVZJEWWZFR-UHFFFAOYSA-N
InChI: InChI=1S/C16H18FN3O2/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11/h3-9,19H,2,10,18H2,1H3,(H,20,21)
Attribute [CAS No.] 150812-12-7 [Formula] C16H18FN3O2 [Molecular] 303.3314232 [Chem Name] ethyl N-[2-amino-4-[(4-fluorophenyl)methylamino]phenyl]carbamate [Synonym] Retigabine; D-23129 [EINECS] 629-886-2 [Storage] Sealed in dry. 2-8°C [MDL No.] MFCD04307735 [Form] White to light brown powder
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