Name：Trametinib

Catalog No.：
BCM002124

Chem Name：
Trametinib

Synonym：
Trametinib; N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide; UNII-33E86K87QN; Mekinist;

CAS No.：
871700-17-3

MDL No.：
MFCD17215075

Formula：
C26H23FIN5O4

Molecular：
615.40

Form：
White solid

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SKU	Specification	Brand	Prices	Stock	Cart
BCM002124-1G	1g, Purity:98%	BCM	$540	2	Add Cart
BCM002124-5G	5g, Purity:99%	BCM	$1888	2	Add Cart
BCM002124-100MG	100mg, Purity:98%	BCM	$149	2	Add Cart
BCM002124-250MG	250mg, Purity:98%	BCM	$220	2	Add Cart

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Trametinib (GSK1120212, JTP-74057, Mekinist) is a highly specific and effective MEK1/2 inhibitor, with IC50 of 0.92 nM/1.8 nM in cell-free tests, and has no inhibitory activity against c-Raf, B-Raf, and ERK1/2. Trametinib can activate autophagy and induce apoptosis.

Brand: BCM

Solubility: Soluble in DMSO (up to 20 mg/ml)

Melting Point: 300-301 °C

Attribute

[Chem Name] Trametinib

[Synonym] Trametinib; N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide; UNII-33E86K87QN; Mekinist;

[CAS No.] 871700-17-3

[MDL No.] MFCD17215075

[Formula] C26H23FIN5O4

[Molecular] 615.40

[Form] White solid

Attribute
[Chem Name]	Trametinib
[Synonym]	Trametinib; N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide; UNII-33E86K87QN; Mekinist;
[CAS No.]	871700-17-3
[MDL No.]	MFCD17215075
[Formula]	C26H23FIN5O4
[Molecular]	615.40
[Form]	White solid