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Dolasetron(MDL-73147EF) is a highly specific and selective serotonin 5-HT3 receptor antagonist. It has minimal activity at other known serotonin receptors, and has low affinity for dopamine receptors.
Brand: BCM
Signaling Pathways: GPCR/G Protein; Neuroscience
Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.
Melting Point: 278 ºC
Boiling Point: 535.1±50.0 °C(Predicted)
pKa: 15.36±0.30(Predicted)
Isomeric SMILES: C1[C@@H]2CC(C[C@H]3N2CC(=O)C1C3)OC(=O)C4=CNC5=CC=CC=C54
InChIKey: UKTAZPQNNNJVKR-AKJUYKBHSA-N
InChI: InChI=1S/C19H20N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,20H,5-8,10H2/t11?,12-,13+,14?
Attribute [CAS No.] 115956-12-2 [Formula] C19H20N2O3 [Molecular] 324.37 [Chem Name] [(3S,7R)-10-oxo-8-azatricyclo[5.3.1.03,8]undecan-5-yl] 1H-indole-3-carboxylate [Synonym] Dolasetron [Storage] Sealed in dry, 2-8°C [MDL No.] MFCD00865542 [Form] White solid
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