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Ipatasertib (GDC-0068) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with an IC50 of 5 nM/18 nM/8 nM in a cell-free assay, 620 times more selective than for PKA. Phase 2.
Brand: BCM
Melting Point: >106°C (dec.)
Solubility: Soluble in DMSO. Insoluble in Water.
Attribute [Chem Name] GDC0068 [Synonym] (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone [CAS No.] 1001264-89-6 [Formula] C24H32ClN5O2 [Molecular] 458.00 [MDL No.] MFCD22124514 [Form] White powder [Storage] Hygroscopic, Refrigerator, under inert atmosphere
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