WZ4002 is a novel, mutation-selective EGFR inhibitor with IC50 of 2 nM/8 nM on EGFR(L858R)/ T790M. It did not inhibit ERBB2 phosphorylation (T798I).

 

Brand: BCM

 

pKa: 12.78±0.70(Predicted)

 

Solubility: ≥24.7 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

 

Attribute
[CAS No.]	1213269-23-8
[Formula]	C25H27ClN6O3
[Molecular]	494.97
[Chem Name]	N-(3-((5-Chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide
[Synonym]	WZ4002
[Storage]	Sealed in dry. Store in freezer, under -20°C
[EINECS]	206-141-6
[MDL No.]	MFCD16621244
[Form]	Solid

Goods Tag