Dovitinib (TKI258) Lactate is the lactate of Dovitinib, a multi-target PTK inhibitor that targets Class III (FLT3/c-Kit) lactate with an IC50 of 1 nM/2 nM. It is also effective against Class IV (FGFR1/3) and Class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, and is less effective against InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.

 

Brand: BCM

 

Solubility: Soluble in DMSO and Water.

 

Attribute
[Chem Name]	Dovitinib (TKI258) Lactate
[CAS No.]	915769-50-5
[Formula]	C24H29FN6O5
[Molecular]	500.531
[EINECS]	691-732-5
[MDL No.]	MFCD22422458
[Form]	Yellow to light yellow powder

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