ML167 (CID 44968231) is a highly selective inhibitor of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM, 10 times more selective than similar kinases Clk1-3 and Dyrk1A/1B.

 

Brand: BCM

 

Target: DYRK; CDK

 

Signaling Pathways: Tyrosine Kinase/Adaptors; Cell Cycle/Checkpoint

 

Boiling Point: 531.8±45.0 °C at 760 mmHg

 

Flashing Point: 275.4±28.7 °C

 

Solubility: Soluble in DMSO; Soluble in Ethanol (warmed with 50ºC water bath). Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: CC1=CC=C(O1)CNC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CO  

 

InChIKey: ROCFOIBAEVAOLQ-UHFFFAOYSA-N  

 

InChI: InChI=1S/C19H17N3O3/c1-12-2-4-14(24-12)9-20-19-16-8-13(3-6-17(16)21-11-22-19)18-7-5-15(10-23)25-18/h2-8,11,23H,9-10H2,1H3,(H,20,21,22)

 

Attribute
[CAS No.]	1285702-20-6
[Formula]	C19H17N3O3
[Molecular]	335.36
[Chem Name]	[5-[4-[(5-methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol
[Synonym]	ML167; CID 44968231
[Storage]	Sealed in dry. Store in freezer, under -20°C
[EINECS]	808-432-9
[MDL No.]	MFCD27978379
[Form]	off-white to gray to brown powder

Goods Tag