A66 is a potent specific p110α inhibitor with an IC50 of 32 nM in cell-free tests, and its action on p110α is more than 100 times more selective than that of other Class I PI3K subtypes.

Brand: BCM

 

pKa: 6.27±0.70(Predicted)

 

GHS: GHS07

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

Isomeric SMILES: CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CSC(=N3)C(C)(C)C  

 

InChIKey: HBPXWEPKNBHKAX-NSHDSACASA-N  

 

InChI: InChI=1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24)/t11-/m0/s1

 

Attribute
[CAS No.]	1166227-08-2
[Formula]	C17H23N5O2S2
[Molecular]	393.53
[Chem Name]	(2S)-1-N-[5-(2-tert-butyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
[Synonym]	A66
[Storage]	Sealed in dry. Store in freezer, under -20°C
[MDL No.]	MFCD22378485
[Form]	Solid

Goods Tag