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Pemafibrate, also known as (R)-K 13675, is a PPAR alpha agonist. (R)-K-13675 decreases the secretion of inflammatory markers without affecting cell proliferation or tube formation. Peroxisome proliferator-activated receptor-alpha (PPAR-alpha) is a key regulator of lipid and glucose metabolism and has been implicated in inflammation. (R)-K-13675 was associated with the inhibition of inflammatory responses without affecting cell proliferation or angiogenesis, and subsequently may induce an anti-atherosclerotic effect.
Brand: BCM
Boiling Point: 676.7±65.0 °C(Predicted)
Solubility: Chloroform (Slightly), Methanol (Slightly)
Drug Formulation: This drug may be formulated in DMSO
InChi Key: ZHKNLJLMDFQVHJ-RUZDIDTESA-N
Attribute [Chem Name] (R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid [Synonym] K-877; K877; K 877; (R)-K 13675; (R)-K13675; (R)K-13675; Pemafibrate [CAS No.] 848259-27-8 [MDL No.] MFCD30533427 [Formula] C28H30N2O6 [Molecular] 490.55 [Form] White to Off-white Solid powder [Storage] Refrigerator
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