BGT226 is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BGT226 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane, increasing mitochondrial membrane permeability; apoptotic cell death may ensue. Bax is a member of the proapoptotic Bcl2 family of proteins.

 

Brand: BCM

 

Solubility: Soluble in DMSO. Insoluble in water.

 

InChi Key: BMMXYEBLEBULND-UHFFFAOYSA-N

 

Attribute
[Chem Name]	8-(6-methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one
[Synonym]	BGT226; BGT 226; BGT-226; NVP-BGT226; NVP-BGT-226; NVP-BGT 226.
[CAS No.]	915020-55-2
[MDL No.]	MFCD22376639
[Formula]	C28H25F3N6O2
[Molecular]	534.53
[Form]	Solid powder

Goods Tag