Chiauranib (CS2164) selectively inhibits a variety of kinase targets, Including aurora B kinase (AURKB), colony-stimulating factor 1 receptor, CSF1R) and vascular endothelial growth factor receptor, Among the platelet derived growth factor receptor (PDGFR)/ c-Kit, platelet derived growth factor receptor (PDGFR)/ C-KIT inhibits the rapid proliferation of tumor cells, enhances anti-tumor immunity, and inhibits tumor angiogenesis, thus achieving anti-tumor efficacy.

 

Brand: BCM

 

Boiling Point: 604.6±50.0 °C(Predicted)

 

pKa: 12.77±0.70(Predicted)

 

Solubility: Soluble in DMSO : 62.5 mg/mL (143.52 mM; Need ultrasonic). Insoluble in Water.

 

InChi Key: BRKWREZNORONDU-UHFFFAOYSA-N

 

Attribute
[Chem Name]	1-Naphthalenecarboxamide, N-(2-aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-
[Synonym]	Chiauranib，CS2164
[CAS No.]	1256349-48-0
[MDL No.]	MFCD34179475
[Formula]	C27H21N3O3
[Molecular]	435.47
[Form]	White solid powder

Goods Tag