LY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases. LY3000328 is currently in clinical trials. Cathepsin S (Cat S) plays an important role in many pathological conditions, including abdominal aortic aneurysm (AAA). Inhibition of Cat S may provide a new treatment for AAA.

 

Brand: BCM

 

Boiling Point: 701.6±60.0 °C at 760 mmHg

 

Flashing Point: 378.1±32.9 °C

 

Solubility: Soluble in DMSO; soluble in Ethnol. Insoluble in Water.

 

InChi Key: NDEBZCZEAVMSQF-GOTSBHOMSA-N

 

Attribute
[Chem Name]	(3R,4S)-4-(4-Fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl)chroman-3-yl methylcarbamate
[Synonym]	LY3000328; Z-FL-COCHO; Cathepsin S inhibitor
[CAS No.]	1373215-15-6
[MDL No.]	MFCD04974155
[Formula]	C25H29FN4O5
[Molecular]	484.52
[Form]	Solid powder

Goods Tag