Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.

 

Brand: BCM

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Stability: Hygroscopic

 

Attribute
[Chem Name]	(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
[Synonym]	SB-497115-GR; Eltrombopag Olamine； Unii-4U07F515
[CAS No.]	496775-62-3
[EINECS]	629-876-8
[MDL No.]	MFCD22380664
[Formula]	C27H29N5O5
[Molecular]	503.56
[Form]	Dark Red to Very Dark Red Solid
[Storage]	Under inert gas (nitrogen or Argon) at 2–8 °C

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