IM156 (HL156A), a metformin derivative, is also a potent activator of AMPK, enhancing AMPK phosphorylation. IM156 can prevent oxidative phosphorylation (OXPHOS) by inhibiting complex I and increase cell apoptosis. IM156 can improve various types of fibrosis and inhibit tumors.

 

Brand: BCM

 

Solubility: Soluble in DMSO; soluble in Ethanol (warmed with 50ºC water bath). Insoluble in Water.

 

Isomeric SMILES: C1CCN(C1)/C(=N/C(=NC2=CC=C(C=C2)OC(F)(F)F)N)/N  

 

InChIKey: NGFUHJWVBKTNOE-UHFFFAOYSA-N  

 

InChI: InChI=1S/C13H16F3N5O/c14-13(15,16)22-10-5-3-9(4-6-10)19-11(17)20-12(18)21-7-1-2-8-21/h3-6H,1-2,7-8H2,(H4,17,18,19,20)

 

Attribute
[Chem Name]	N'-[N'-[4-(trifluoromethoxy)phenyl]carbamimidoyl]pyrrolidine-1-carboximidamide
[Synonym]	IM156; HL156A
[CAS No.]	1422365-93-2
[MDL No.]	MFCD32856762
[Formula]	C13H16F3N5O
[Molecular]	315.29
[Form]	Solid powder
[Storage]	Keep in dark place. Inert atmosphere, 2-8°C

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