TCS PIM-1 1 (SC 204330) is a potent and selective ATP-competitive Pim-1 kianse inhibitor with an IC50 value of 50 nM. Good selectivity for Pim-2 and MEK1/MEK2 (IC50> 20000 nM).

 

Brand: BCM

 

Boiling Point: 592.6±50.0 °C(Predicted)

 

pKa: 6.93±0.10(Predicted)

 

Solubility: Soluble in DMSO.

 

Isomeric SMILES: C1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=C(C=CC(=C3)Br)O)C#N  

 

InChIKey: SVSYJTYGPLVUOZ-UHFFFAOYSA-N  

 

InChI: InChI=1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9,22H,(H,21,23)  

 

Attribute
[Chem Name]	6-(5-Bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
[Synonym]	TCS PIM-1 1; SC 204330
[CAS No.]	491871-58-0
[MDL No.]	MFCD00276275
[Formula]	C18H11BrN2O2
[Molecular]	367.2
[Form]	A solid
[Storage]	Keep in dark place. Inert atmosphere. Room temperature

Goods Tag