Dubs-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs) with an IC50 of 0.85 μM against USP8.

 

Brand: BCM

 

IC50 & Target: IC50: 0.24 μM (USP8)

 

Signaling Pathways: Ubiquitination; DNA Damage/DNA Repair; Cell Cycle/Checkpoint

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: C1=CC=C(C=C1)CO/N=C/2\C3=CC=CC=C3C4=NC(=C(N=C42)C#N)C#N  

 

InChIKey: GKOWDIBLCDZJHF-NCELDCMTSA-N  

 

InChI: InChI=1S/C20H11N5O/c21-10-16-17(11-22)24-20-18(23-16)14-8-4-5-9-15(14)19(20)25-26-12-13-6-2-1-3-7-13/h1-9H,12H2/b25-19+

 

Attribute
[Chem Name]	(9E)-9-phenylmethoxyiminoindeno[1,2-b]pyrazine-2,3-dicarbonitrile
[Synonym]	Dubs-IN-1
[CAS No.]	924296-18-4
[MDL No.]	MFCD11977746
[Formula]	C20H11N5O
[Molecular]	337.33
[Form]	Solid powder
[Storage]	Sealed in dry. Stored under -20°C

Goods Tag