DBeQ (JRF 12) is a selective, potent, reversible, ATP-competitive inhibitor of p97 with an IC50 of 1.5 μM.

 

Brand: BCM

 

Melting Point: 149 °C

 

Boiling Point: 573.1±52.0 °C(Predicted)

 

pKa: 7.78±0.30(Predicted)

 

Signaling Pathways: Ubiquitination; Autophagy; Apoptosis

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

Isomeric SMILES: C1=CC=C(C=C1)CNC2=NC(=NC3=CC=CC=C32)NCC4=CC=CC=C4  

 

InChIKey: QAIMUUJJAJBPCL-UHFFFAOYSA-N  

 

InChI: InChI=1S/C22H20N4/c1-3-9-17(10-4-1)15-23-21-19-13-7-8-14-20(19)25-22(26-21)24-16-18-11-5-2-6-12-18/h1-14H,15-16H2,(H2,23,24,25,26)

 

Attribute
[Chem Name]	2-N,4-N-dibenzylquinazoline-2,4-diamine
[Synonym]	DBeQ; JRF 12
[CAS No.]	177355-84-9
[MDL No.]	MFCD03691820
[Formula]	C22H20N4
[Molecular]	340.42
[Form]	White to beige powder
[Storage]	Keep in dark place. Sealed in dry, 2-8°C

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