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Thalidomide-NH-C4-NH-Boc is a novel, effective and selective Bromodomain-containing protein 4 (Bromodomain-containing protein 4, Thalidomide-NH-C4-NH-BOC). BRD4) and Bromodomain-containing protein 2 (BRD2) degraders, which can be used to develop therapies to treat cancer.
Brand: BCM
Target: E3 Ligase Ligand-Linker Conjugates
Melting Point: 704.0±60.0 °C(Predicted)
pKa: 10.75±0.40(Predicted)
Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.
Isomeric SMILES: CC(C)(C)OC(=O)NCCCCNC1=CC=CC2=C1C(=O)N(C2=O)C3CCC(=O)NC3=O
InChIKey: OYPNLZMEXLFKLB-UHFFFAOYSA-N
InChI: InChI=1S/C22H28N4O6/c1-22(2,3)32-21(31)24-12-5-4-11-23-14-8-6-7-13-17(14)20(30)26(19(13)29)15-9-10-16(27)25-18(15)28/h6-8,15,23H,4-5,9-12H2,1-3H3,(H,24,31)(H,25,27,28)
Attribute [Chem Name] tert-butyl N-[4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butyl]carbamate [Synonym] Thalidomide-NH-C4-NH-Boc [CAS No.] 2093388-52-2 [MDL No.] MFCD32671351 [Formula] C22H28N4O6 [Molecular] 444.48 [Form] Solid [Storage] 2-8°C, protect from light
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