RU-301 is an inhibitor of the pan-Tam receptor (Axl, Tyro3 and Mertk), which can block the dimerization site of the Axl receptor with corresponding Kd value of 12 μM and IC50 value of 10 μM.

 

Brand: BCM

 

Boiling Point: 661.0±55.0 °C(Predicted)

 

pKa: 13.86±0.46(Predicted)

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

Isomeric SMILES: CC1=NOC(=C1)CSC2=CC=CC=C2C(=O)NCCNC3=C(C=C(C=C3)C(F)(F)F)[N+](=O)[O-]  

 

InChIKey: BPHPWPNHNGXNPR-UHFFFAOYSA-N  

 

InChI: InChI=1S/C21H19F3N4O4S/c1-13-10-15(32-27-13)12-33-19-5-3-2-4-16(19)20(29)26-9-8-25-17-7-6-14(21(22,23)24)11-18(17)28(30)31/h2-7,10-11,25H,8-9,12H2,1H3,(H,26,29)

 

Attribute
[Chem Name]	2-[(3-methyl-1,2-oxazol-5-yl)methylsulfanyl]-N-[2-[2-nitro-4-(trifluoromethyl)anilino]ethyl]benzamide
[Synonym]	RU-301
[CAS No.]	1110873-99-8
[MDL No.]	MFCD11802385
[Formula]	C21H19F3N4O4S
[Molecular]	480.46
[Form]	Solid
[Storage]	Store at -20°C

Goods Tag