NH125 is a selective eEF-2 kinase inhibitor with an IC50 of 60 nM, 125 times more selective than PKC, PKA and CaMKII, and it is also a potent histidine kinase inhibitor.

 

Brand: BCM

 

Target: Antibacterial; Antifungal; PKA; PKC; Virus Protease; CaMK; Autophagy

 

Signaling Pathways: Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Neuroscience; Tyrosine Kinase/Adaptors

 

Melting Point: 88.2-94.9 °C

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

Isomeric SMILES: CCCCCCCCCCCCCCCCN1C=C[N+](=C1C)CC2=CC=CC=C2.[I-]  

 

InChIKey: RVWOHCBHAGBLLT-UHFFFAOYSA-M  

 

InChI: InChI=1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1

 

Attribute
[Chem Name]	1-benzyl-3-hexadecyl-2-methylimidazol-1-ium;iodide
[Synonym]	NH125; NH-125
[CAS No.]	278603-08-0
[MDL No.]	MFCD07370143
[Formula]	C27H45N2.I
[Molecular]	524.567
[Form]	White to off-white solid
[Storage]	Keep in dark place. Inert atmosphere. Room temperature

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