STO-609 is a specific inhibitor of CaM-KK, inhibiting the activity of CAM-Kkα and CAM-Kkβ with Ki values of 80 ng/ml and 15 ng/ml, respectively, and inhibiting their self-phosphorylation activity. STO-609 can inhibit AMPKK activity and inhibit autophagy.

 

Brand: BCM

 

Target: CaM-KKα:0.25 μM(Ki), CaM-KKβ:47 nM(Ki)

 

Melting Point: >300 °C

 

Boiling Point: 716.9±62.0 °C(Predicted)

 

pKa: 2.65±0.20(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Ethanol; insoluble in Water.

 

Isomeric SMILES: C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O  

 

InChIKey: MYKOWOGZBMOVBJ-UHFFFAOYSA-N  

 

InChI: InChI=1S/C19H10N2O3/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18/h1-9H,(H,23,24)

 

Attribute
[Chem Name]	11-oxo-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(20),2,4,6,8,12,14,16,18-nonaene-17-carboxylic acid
[Synonym]	STO-609; STO-609-acetic acid
[CAS No.]	52029-86-4
[MDL No.]	MFCD06411456
[Formula]	C19H10N2O3
[Molecular]	314.29
[Form]	Solid
[Storage]	Sealed in dry, 2-8°C

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