SU5402 is a potent multi-target receptor kinase inhibitor with an IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.

 

Brand: BCM

 

Target: VEGFR; FGFR; PDGFR

 

Signaling Pathways: Angiogenesis; Tyrosine Kinase/Adaptors

 

Melting Point: >222°C (dec.)

 

Boiling Point: 592.6±50.0 °C(Predicted)

 

pKa: 4.60±0.10(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O  

 

InChIKey: JNDVEAXZWJIOKB-JYRVWZFOSA-N  

 

InChI: InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-

 

Attribute
[Chem Name]	3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
[Synonym]	SU5402; SU 5402; SU-5402
[CAS No.]	215543-92-3
[MDL No.]	MFCD08235144
[Formula]	C17H16N2O3
[Molecular]	296.32
[Form]	Light orange to dark orange powder
[Storage]	Keep in dark place. Sealed in dry, 2-8°C

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