JBSNF-000088 (6-Methoxynicotinamide), a Nicotinamide (NA) analogue, is a potent inhibitor of Nicotinamide N-methyltransferase (NNMT). The IC50 values for human NNMT(hNNMT), monkey NNMT(mkNNMT), and mouse NNMT(mNNMT) are 1.8 µM, 2.8 µM, and 5.0 µM.

 

Brand: BCM

 

Target: mouse NNMT:5.0 µM (IC50), human NNMT:1.8 µM (IC50), monkey NNMT:2.8 µM (IC50)

 

Melting Point: 178-180°C

 

Boiling Point: 301.6±22.0 °C(Predicted)

 

pKa: 15.17±0.50(Predicted)

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: COC1=NC=C(C=C1)C(=O)N  

 

InChIKey: KXDSMFBEVSJYRF-UHFFFAOYSA-N  

 

InChI: InChI=1S/C7H8N2O2/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10)

 

Attribute
[Chem Name]	6-methoxypyridine-3-carboxamide
[Synonym]	JBSNF-000088; 6-Methoxynicotinamide
[CAS No.]	7150-23-4
[EINECS]	604-604-1
[MDL No.]	MFCD00229166
[Formula]	C7H8N2O2
[Molecular]	152.15
[Form]	Off-White to Pale Beige
[Storage]	Sealed in dry. Room Temperature

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