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Didox (3, 4-Dihydroxy-Benzohydroxamic acid) is a synthetic inhibitor of ribonucleotide reductase (RR) derived from polyhydroxy-substituted benzohydroxamic acids. Didox inhibits the proliferation of tamoxifen-resistant breast cancer cells.
Brand: BCM
Target: DNA/RNA Synthesis
Signaling Pathways: Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Melting Point: 207 °C
pKa: 8.16±0.20(Predicted)
Solubility: Soluble in DMSO; soluble in Water; soluble in Ethanol.
Isomeric SMILES: C1=CC(=C(C=C1C(=O)NO)O)O
InChIKey: QJMCKEPOKRERLN-UHFFFAOYSA-N
InChI: InChI=1S/C7H7NO4/c9-5-2-1-4(3-6(5)10)7(11)8-12/h1-3,9-10,12H,(H,8,11)
Attribute [Chem Name] N,3,4-trihydroxybenzamide [Synonym] Didox; 3,4-dihydroxy-benzohydroxamic acid [CAS No.] 69839-83-4 [MDL No.] MFCD01667810 [Formula] C7H7NO4 [Molecular] 169.13 [Form] A crystalline solid [Storage] Inert atmosphere. Store in freezer, under -20°C
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