CA-170 (AUPM-170, PD-1-IN-1) is a potent oral inhibitor of the immune checkpoint regulator PD-L1 (programmed cell death ligand-1) and VISTA (T-cell-activated V-domain immunoglobulin (Ig)). Inhibitor). CA-170 has anti-tumor properties.

 

Brand: BCM

 

Target: PD-L1

 

pKa: 3.42±0.10(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: C[C@H]([C@@H](C(=O)O)NC(=O)N[C@@H](CC(=O)N)C1=NC(=NO1)[C@H](CO)N)O  

 

InChIKey: HFOBENSCBRZVSP-LKXGYXEUSA-N  

 

InChI: InChI=1S/C12H20N6O7/c1-4(20)8(11(22)23)16-12(24)15-6(2-7(14)21)10-17-9(18-25-10)5(13)3-19/h4-6,8,19-20H,2-3,13H2,1H3,(H2,14,21)(H,22,23)(H2,15,16,24)/t4-,5+,6+,8+/m1/s1

 

Attribute
[Chem Name]	(2S,3R)-2-[[(1S)-3-amino-1-[3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl]-3-oxopropyl]carbamoylamino]-3-hydroxybutanoic acid
[Synonym]	CA-170; AUPM-170
[CAS No.]	1673534-76-3
[MDL No.]	MFCD30738000
[Formula]	C12H20N6O7
[Molecular]	360.32
[Form]	Solid Powder
[Storage]	Store at -20°C

Goods Tag