SW-044248 is a non-classical Topo1 inhibitor with selective toxic effects on non-small cell lung cancer cells.

 

Brand: BCM

 

Target: Topoisomerase

 

Signaling Pathways: DNA Damage/DNA Repair

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: CCC(C(=O)NC1=CC=CC=C1OC)SC2=NC3=C(C4=CC=CC=C4N3CC)N=N2  

 

InChIKey: PEVRGVRHMMZNGI-UHFFFAOYSA-N  

 

InChI: InChI=1S/C22H23N5O2S/c1-4-18(21(28)23-15-11-7-9-13-17(15)29-3)30-22-24-20-19(25-26-22)14-10-6-8-12-16(14)27(20)5-2/h6-13,18H,4-5H2,1-3H3,(H,23,28)

 

Attribute
[Chem Name]	2-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-N-(2-methoxyphenyl)butanamide
[Synonym]	SW-044248
[CAS No.]	522650-83-5
[MDL No.]	MFCD03487851
[Formula]	C22H23N5O2S
[Molecular]	421.52
[Form]	White to beige powder
[Storage]	Sealed in dry, 2-8°C

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