TC-H 106 (Pimelic Diphenylamide 106) is a slow, tightly bound Class I inhibitor of histone deacetylases(HDAC). The Ki values of HDAC1, HDAC2 and HDAC3 are 148 nM, about 102 nM and 14 nM, respectively.

 

Brand: BCM

 

Target: HDAC

 

Signaling Pathways: Chromatin/Epigenetic; DNA Damage/DNA Repair

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: CC1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N  

 

InChIKey: WTKBRPXPNAKVEQ-UHFFFAOYSA-N  

 

InChI: InChI=1S/C20H25N3O2/c1-15-11-13-16(14-12-15)22-19(24)9-3-2-4-10-20(25)23-18-8-6-5-7-17(18)21/h5-8,11-14H,2-4,9-10,21H2,1H3,(H,22,24)(H,23,25) 

 

Attribute
[Chem Name]	N'-(2-aminophenyl)-N-(4-methylphenyl)heptanediamide
[Synonym]	TC-H 106; Pimelic Diphenylamide 106
[CAS No.]	937039-45-7
[MDL No.]	MFCD17010287
[Formula]	C20H25N3O2
[Molecular]	339.43
[Form]	Beige to Yellow Solid Powder
[Storage]	Keep in dark place. Inert atmosphere, 2-8°C

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