Coluracetam (BCI-540, MKC-231) is a nootropic drug with cognitive enhancement and neuroprotective effects.

 

Brand: BCM

 

Target: iGluR; AChR

 

Signaling Pathways: Membrane transporter/Ion channel; Neuroscience

 

In Vitro: Treatment with MKC-231 increased Vmax of HACU and Bmax of [3H]-HC-3 binding 1.6 and 1.7-fold, respectively.?In studies of [3H]-MKC-231 binding and Biacore analysis, MKC-231 showed noticeable affinity for cloned high-affinity choline transporters (CHT1).

 

Boiling Point: 634.1±55.0 °C(Predicted)

 

pKa: 12.01±0.20(Predicted)

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS09

 

Isomeric SMILES: CC1=C(OC2=NC3=C(CCCC3)C(=C12)NC(=O)CN4CCCC4=O)C  

 

InChIKey: PSPGQHXMUKWNDI-UHFFFAOYSA-N  

 

InChI: InChI=1S/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23) 

 

Attribute
[Chem Name]	N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide
[Synonym]	Coluracetam; MKC-231; BCI-540
[CAS No.]	135463-81-9
[EINECS]	1308068-626-2
[MDL No.]	MFCD00901416
[Formula]	C19H23N3O3
[Molecular]	341.4
[Form]	Solid Powder
[Storage]	Sealed in dry. Room Temperature

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