FSEN1 is a potent non-competitive FSP1 inhibitor with an IC50 value of 313 nM. It triggers iron death in cancer cells by inhibiting FSP1 and could be used in cancer research.

 

Brand: BCM

 

pKa: 6.56±0.10(Predicted)

 

Solubility: Soluble in DMSO; Soluble in Ethanol. Insoluble in Water.

 

Isomeric SMILES: COC1=CC=C(C=C1)N2CCN(CC2)CC3=CN4C(=NN=C4S3)C5=CC=C(C=C5)Br  

 

InChIKey: JGXIXBKKDUNARN-UHFFFAOYSA-N  

InChI: InChI=1S/C22H22BrN5OS/c1-29-19-8-6-18(7-9-19)27-12-10-26(11-13-27)14-20-15-28-21(24-25-22(28)30-20)16-2-4-17(23)5-3-16/h2-9,15H,10-14H2,1H3

 

Attribute
[Chem Name]	3-(4-bromophenyl)-6-[[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-[1,3]thiazolo[2,3-c][1,2,4]triazole
[Synonym]	FSEN1
[CAS No.]	862808-01-3
[MDL No.]	MFCD05897677
[Formula]	C22H22BrN5OS
[Molecular]	484.41
[Form]	Solid Powder
[Storage]	Sealed in dry. Stored at -20°C.

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