Fialuridine(FIAU, DRG-0098, NSC 678514) is a nucleoside analogue with antiviral activity. Block human cytomegalovirus, hepatitis B and herpes simplex virus DNA synthesis.

 

Brand: BCM

 

Melting Point: 216-217°C

 

Target: DNA/RNA Synthesis

 

In Vitro: Fialuridine (FIAU) blocks DNA synthesis in human cytomegalovirus and hepatitis B, as well as herpes simplex

 

pKa: 7.94±0.10(Predicted)

 

Solubility: Solube in DMSO; Soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: C1=C(C(=O)NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F)I  

 

InChIKey: IPVFGAYTKQKGBM-BYPJNBLXSA-N  

 

InChI: InChI=1S/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5+,6-,8-/m1/s1

 

Attribute
[Chem Name]	1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
[Synonym]	Fialuridine; FIAU; DRG-0098; NSC 678514
[CAS No.]	69123-98-4
[EINECS]	1312995-182-4
[MDL No.]	MFCD00866922
[Formula]	C9H10FIN2O5
[Molecular]	372.09
[Form]	White to beige powder
[Storage]	Keep in dark place. Sealed in dry. Store in freezer, under -20°C

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