BIA (TMBIM6 antagonist BIA) is a potential TMBIM6 antagonist that blocks the interaction of TMBIM6 and mTORC2, ultimately blocking AKT activation and cancer progression.

 

Brand: BCM

 

Target: Phosphatase; mTOR

 

Signaling Pathways: Metabolism; PI3K/Akt/mTOR signaling

 

Melting Point: 152 °C(Solv: ethanol (64-17-5))

 

Boiling Point: 482.1±45.0 °C(Predicted)

 

pKa: -0.21±0.10(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; Insoluble in Ethanol.

 

Isomeric SMILES: C1=CC=C(C(=C1)C(=O)/C=C/C2=CC(=CC=C2)[N+](=O)[O-])N  

 

InChIKey: LRMPAVQDWGDIBD-CMDGGOBGSA-N  

 

InChI: InChI=1S/C15H12N2O3/c16-14-7-2-1-6-13(14)15(18)9-8-11-4-3-5-12(10-11)17(19)20/h1-10H,16H2/b9-8+

 

Attribute
[Chem Name]	(E)-1-(2-aminophenyl)-3-(3-nitrophenyl)prop-2-en-1-one
[Synonym]	BIA; TMBIM6 antagonist BIA
[CAS No.]	134271-74-2
[Formula]	C15H12N2O3
[Molecular]	268.27
[Form]	Solid Powder
[Storage]	Keep in dark place. Inert atmosphere. Room temperature

Goods Tag