Lupenone (UP-20 (29)-en-3-one, lupeone) is an isolated compound with antioxidant, anti-inflammatory and anti-diabetic activities. Lupenone can protect SH-SY5y cells from METH induced neuronal apoptosis through PI3K/Akt pathway.

 

Brand: BCM

 

Target: Phosphatase; Parasite

 

Signaling Pathways: Metabolism; Microbiology/Virology

 

In Vivo: Lupenone significantly decreased acute and subacute inflammation in mice as well as the IL-1β and IFN-γ levels in the pancreas of diabetic rats.

 

Melting Point: 165-167°C

 

Boiling Point: 485.7±14.0 °C(Predicted)

 

Solubility: Soluble in DMSO; Soluble in Ethnaol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CCC(=O)C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)C)C  

 

InChIKey: GRBHNQFQFHLCHO-BHMAJAPKSA-N  

 

InChI: InChI=1S/C30H48O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-23,25H,1,9-18H2,2-8H3/t20-,21+,22-,23+,25+,27+,28-,29+,30+/m0/s1

 

Attribute
[Chem Name]	(1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysen-9-one
[Synonym]	Lupenone; Lup-20(29)-en-3-one; lupeone
[CAS No.]	1617-70-5
[MDL No.]	MFCD00083578
[Formula]	C30H48O
[Molecular]	424.7
[Form]	White solid
[Storage]	Keep in dark place. Sealed in dry, 2-8°C

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