XL092 (JUN04542) is an ATP competitive inhibitor of multiple RTK, including MET, VEGFR2, AXL, and MER, with IC50 values of 15 nM, 1.6 nM, 3.4 nM, and 7.2 nM, respectively, in cell-based assays.

 

Brand: BCM

 

Target: VEGFR; c-Met/HGFR; TAM Receptor

 

Signaling Pathways: Angiogenesis; Tyrosine Kinase/Adaptors

 

Boiling Point: 840.4±65.0 °C(Predicted)

 

pKa: 13.14±0.46(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; Insoluble in Ethanol.

 

Isomeric SMILES: CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F  

 

InChIKey: JSPCKALGNNVYOO-UHFFFAOYSA-N  

 

InChI: InChI=1S/C29H25FN4O5/c1-31-26(35)22-15-21-23(16-25(22)38-2)32-14-11-24(21)39-20-9-7-19(8-10-20)34-28(37)29(12-13-29)27(36)33-18-5-3-17(30)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,35)(H,33,36)(H,34,37) 

 

Attribute
[Synonym]	XL092; JUN04542; CL-092
[CAS No.]	2367004-54-2
[MDL No.]	MFCD34179545
[Formula]	C29H25FN4O5
[Molecular]	528.53
[Form]	Solid Powder
[Storage]	Keep in dark place. Inert atmosphere. Room temperature
[Chem Name]	1-N'-(4-fluorophenyl)-1-N-[4-[7-methoxy-6-(methylcarbamoyl)quinolin-4-yl]oxyphenyl]cyclopropane-1,1-dicarboxamide

Goods Tag