Pimicotinib (ABSK021) is an oral bioavailable colony stimulating factor 1 receptor (CSF1R) inhibitor. It enhances the anti-tumor T cell immune response and inhibits the proliferation of tumor cells, and has potential immunomodulatory and anti-tumor activities.

 

Brand: BCM

 

Solubility: Soluble in DMSO; Soluble in Ethanol. Insoluble in Water.

 

Isomeric SMILES: CC1=C(C=CC(=N1)NC(=O)N2CCC(C2=O)(C)C)OC3=CC(=NC=C3)C4=CN(N=C4)C  

 

InChIKey: NXFPMDWYDKHFMM-UHFFFAOYSA-N  

 

InChI: InChI=1S/C22H24N6O3/c1-14-18(31-16-7-9-23-17(11-16)15-12-24-27(4)13-15)5-6-19(25-14)26-21(30)28-10-8-22(2,3)20(28)29/h5-7,9,11-13H,8,10H2,1-4H3,(H,25,26,30)

 

Attribute
[Chem Name]	3,3-dimethyl-N-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]-2-oxopyrrolidine-1-carboxamide
[Synonym]	Pimicotinib; ABSK021
[CAS No.]	2253123-16-7
[Formula]	C22H24N6O3
[Molecular]	420.47
[Form]	Solid Powder
[Storage]	Stored at -20°C

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